Unusual clinical findings in thrombotic thrombocytopenic purpura
نویسندگان
چکیده
منابع مشابه
Thrombotic thrombocytopenic purpura: MR findings.
Neurologic manifestations occur in over 90% of patients with thrombotic thrombocytopenic purpura. Neuropathologically, thrombi produce occlusion of terminal arterioles and capillaries resulting in diffuse small infarcts. In the great majority of surviving patients, brain CT does not disclose any abnormalities. The authors report a case of thrombotic thrombocytopenic purpura in which brain MR ex...
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Thrombotic thrombocytopenic purpura is a disseminated form of thrombotic microangiopathy. Although most cases are assumed to be idiopathic, its association with malignancy is well-recognized and it usually occurs at the terminal stage of cancer. The condition is characterized by microangiopathic hemolytic anemia and thrombocytopenia. It is generally idiopathic, and its association with adenocar...
متن کاملThrombotic Thrombocytopenic Purpura
Thrombotic microangiopathy comprises a spectrum of clinical and lab findings including microangiopathic hemolytic anemia, thrombocytopenia, and thrombosis of capillary and arterioles. Platelet and hyaline thrombi with complete or partial occlusion of these vessels are integral histopathological findings. These findings are seen irrespective of cause and organ involved. Pathogenesis and prognosi...
متن کاملThrombotic thrombocytopenic purpura.
A 6-year-old boy presented with microangiopathic hemolytic anemia, thrombo-cytopenia, altered sensorium and intractable bleeding. A diagnosis of thrombotic thrombocytopenic purpura was made and the child recovered dramatically after plasmapheresis. Recent developments in the understanding of TTP are reviewed, including the importance of a metaloprotease required to cleave multimers of von Willi...
متن کاملThrombotic Thrombocytopenic Purpura: Diagnosis and Treatment
Thrombotic Thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathic disease, associated with thrombocytopenia and hemolytic anemia. It is caused by an enzymatic dysfunction responsible in cleavage of blood clotting factors. In this study we have tried to review the available approaches in diagnoses of the disease as well as treatment strategies. Based on the what the current review ...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2010
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.2009.07724.x